Fanconi syndromeis a hereditary disease that can be tested with a DNA test. Fanconi syndrome is a defect of proximal renal tubules affecting the resorption of glucose, amino acids, bicarbonate and other substances filtered by the glomeruli. Symptoms include excessive drinking (polydipsia), excessive urination (polyuria), and glucose in the urine (glucosuria.) If Fanconi syndrome is left untreated, muscle wasting, acidosis, and poor condition will occur and dog can die from the disorder.

Inheritance: autosomal recessive - read more

Mutation: FAN1 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.