Canine multifocal retinopathy type 1 (CMR1)

Canine multifocal retinopathy (CMR1) is an autosomal recessive genetic eye disorder similar to Best macular dystrophy in humans. Causative mutation in BEST1 gene generates a premature stop codon, which results in non- functional protein responsible for proper formation of pigment epithelium in retina. Typical clinical findings include multifocal areas of retinal elevation which progress to multifocal areas of outer retinal atrophy. In affected animals, the disease develops before 4 months of age and might progress slowly. Some affected animals do not show symptoms until later in life, but you can discover them early with genetic testing.

Inheritance: autosomal recessiveread more

Mutation: VMD2 gene

Genetic test: The method used forgenetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. Testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.


42.70 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
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