Canine multiple system degeneration (CMSD)

Canine multiple system degeneration (CMSD) is a fatal autosomal recessive hereditary disease. First clinical signs develop at 3 to 6 months of age, and include cranial intention tremors, cerebellar ataxia, goose stepping gait and infrequent falls. Clinical signs become more severe with the hereditary disease progression and include frequent falling episodes, akinesia, and severe postural instability. Affected dogs are usually euthanized by 1-2 years of age.

Inheritance: autosomal recessiveread more

Mutation: SERAC1 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers, and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here


48.80 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
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