Macular corneal dystrophy (MCD)

Macular corneal dystrophy (MCD) is a hereditary disease which can be tested with a DNA test. Macular corneal dystrophy (MCD) is an autosomal recessive inherited disorder that causes progressive visual impairment. This hereditary disease occurs in middle-aged Labrador retrievers that develop cloudy corneas due to an abnormal accumulation of carbohydrates (glycosaminoglycans) in the stroma. This hereditary disease is not painful, slowly progressive and affects both eyes. The vision is reasonably well retained initially, but will reduce over time and detailed vision will be lost, with the condition eventually leading to severe visual impairment. 

Inheritance: autosomal recessive - read more

Mutation: CHST6 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.


48.80 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
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