Shar-Pei auto-inflammatory disease (SPAID) is a hereditary disease which can be tested with a DNA test. Complex disease processes with varying clinical signs characterize auto-inflammatory diseases in dogs. Shar-Pei auto-inflammatory disease (SPAID) is characterised by skin inflammation (dermatitis), periodic fever and arthritis. Additional signs could be otitis, eye inflammation, erythema, thickened and pasty skin, recurrent intestinal inflammations and systemic amyloidosis. Onset of signs of inflammation is variable from 1 up to 12 years of age. 

Inheritance: autosomal dominant (incomplete penetrance) - read more

Mutation: MTBP gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age. 

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.